Methanol → Trifluoroacetic acid

HRID 1206262Notes

Reaction equation

HRID 1206262 reaction equation
[Br:1][c:2]1[n:3][c:4]([NH:15][CH2:12][c:13]2[cH:14][cH:16][c:17]([O:18][CH3:19])[cH:20][c:21]2[O:22][CH3:23])[c:5]([NH:8][CH2:9][C:10](=[O:11])[O:24][CH2:25][CH3:26])[n:6][cH:7]1.[CH3:27][OH:28].[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35]>>[Br:1][c:2]1[n:3][c:4]2[c:5]([n:6][cH:7]1)[NH:8][CH2:9][C:10](=[O:11])[NH:15]2.[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35]

Participants

5

Reactant 3

HCID 887MethanolHCID 6422Trifluoroacetic acidHCID 86696613Ethyl 2-(5-bromo-3-(2,4-dimethoxybenzylamino)pyrazin-2-ylamino)acetate

Product 2

HCID 6422Trifluoroacetic acidHCID 866446447-Bromo-3,4-dihydropyrazino[2,3-B]pyrazin-2(1H)-one

Sources & evidence

ORD record
ord-cd62b60c170444979b249852ea529e1c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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