Potassium Cation → 3-chloro-N-[3-(4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-ylmethoxy)-4-methyl-phenyl]-4-fluoro-benzamide

HRID 1206353Notes

Reaction equation

HRID 1206353 reaction equation
[Br:26][CH2:27][c:28]1[n:29][n:30]([CH3:38])[c:31]2[n:32][cH:33][n:34][c:35]([Cl:37])[c:36]12.[C:20](=[O:21])([O-:22])[O-:23].[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][c:10]([OH:15])[c:11]([CH3:14])[cH:12][cH:13]2)[cH:16][cH:17][c:18]1[F:19].[K+:24].[K+:25]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][c:10]([O:15][CH2:27][c:28]3[n:29][n:30]([CH3:38])[c:31]4[n:32][cH:33][n:34][c:35]([Cl:37])[c:36]34)[c:11]([CH3:14])[cH:12][cH:13]2)[cH:16][cH:17][c:18]1[F:19]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 575815783-chloro-4-fluoro-N-(3-hydroxy-4-methyl-phenyl)-benzamideHCID 575815813-bromomethyl-4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Product 1

HCID 575815883-chloro-N-[3-(4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-ylmethoxy)-4-methyl-phenyl]-4-fluoro-benzamide

Sources & evidence

ORD record
ord-c1e11da4233b4d17a338bf633b2b2cfb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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