Dichloromethane → 3-[[4-(4-amino-3-fluorobenzoyl)-2-methylpiperazin-1-yl]methyl]-N-tert-butylbenzamide
Reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[NH:12][C:13]([c:14]1[cH:15][c:16]([CH2:20][N:21]2[CH:22]([CH3:27])[CH2:23][NH:24][CH2:25][CH2:26]2)[cH:17][cH:18][cH:19]1)=[O:28].[CH2:1]([P:2]([OH:3])(=[O:4])[OH:5])[CH2:6][CH3:7].[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[Cl:47][CH2:48][Cl:49].[NH2:29][c:30]1[c:31]([F:39])[cH:32][c:33]([C:34](=[O:35])[OH:36])[cH:37][cH:38]1>>[C:8]([CH3:9])([CH3:10])([CH3:11])[NH:12][C:13]([c:14]1[cH:15][c:16]([CH2:20][N:21]2[CH:22]([CH3:27])[CH2:23][N:24]([C:34]([c:33]3[cH:32][c:31]([F:39])[c:30]([NH2:29])[cH:38][cH:37]3)=[O:35])[CH2:25][CH2:26]2)[cH:17][cH:18][cH:19]1)=[O:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5287f8e12aba46a695af790c5db5a001
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…