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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1206729Generated: October 27, 2026

Tetrahydrofuran → Methyl 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylate

https://huagongshe.com/reaction/1206729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactant2-Fluoro-4-(methylsulfanyl)anilineHCID 22025617—
ReactantMethyl 2-chloro-5-fluoro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylateHCID 66674383—
ProductMethyl 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylateHCID 66673936—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-bc5d4a94938442c1aa3bd11b1f39fb29
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)