Tetrahydrofuran → Methyl 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylate
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:11][Si:12]([N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cl:21][c:22]1[n:23]([CH3:34])[c:24](=[O:33])[c:25]([F:32])[cH:26][c:27]1[C:28](=[O:29])[O:30][CH3:31].[F:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([S:9][CH3:10])[cH:8]1.[Li+:20]>>[F:1][c:2]1[c:3]([NH:4][c:22]2[n:23]([CH3:34])[c:24](=[O:33])[c:25]([F:32])[cH:26][c:27]2[C:28](=[O:29])[O:30][CH3:31])[cH:5][cH:6][c:7]([S:9][CH3:10])[cH:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bc5d4a94938442c1aa3bd11b1f39fb29
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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