Oxalyl chloride → N-[3-(1-diphenylmethylpiperidin-4-yl)-propyl]-3-(pyridin-3-yl)-acrylamide

HRID 1206842Notes

Reaction equation

HRID 1206842 reaction equation
[Cl:12][C:13]([C:14]([Cl:15])=[O:16])=[O:17].[c:18]1([CH:24]([N:25]2[CH2:26][CH2:27][CH:28]([CH2:31][CH2:32][CH2:33][NH2:34])[CH2:29][CH2:30]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:19][cH:20][cH:21][cH:22][cH:23]1.[n:1]1[cH:2][c:3]([CH:7]=[CH:8][C:9](=[O:10])[OH:11])[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH:7]=[CH:8][C:9](=[O:11])[NH:34][CH2:33][CH2:32][CH2:31][CH:28]2[CH2:27][CH2:26][N:25]([CH:24]([c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[CH2:30][CH2:29]2)[cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 184257323-(1-Diphenylmethylpiperidine-4-yl)-propylamine

Product 1

HCID 54449059N-[3-(1-diphenylmethylpiperidin-4-yl)-propyl]-3-(pyridin-3-yl)-acrylamide

Sources & evidence

ORD record
ord-c82694e5f5dc4329815b09da9aed24e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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