Water → benzyl {1-[5-(2,2-dimethylbutyl)-1-methyl-1H-imidazol-2-yl]-2-[4-(5-fluoropyridin-2-yl)phenyl]ethyl}methylcarbamate
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([c:10]2[n:11]([CH3:21])[c:12]([CH2:15][C:16]([CH2:17][CH3:18])([CH3:19])[CH3:20])[cH:13][n:14]2)[N:22]([C:23]([O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)=[O:32])[CH3:33])[cH:6][cH:7]1.[Br:34][c:35]1[n:36][cH:37][c:38]([F:41])[cH:39][cH:40]1.[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[OH2:48].[Pd:125].[c:106]1([P:107]([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[cH:120][cH:121][cH:122][cH:123][cH:124]1.[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1.[c:68]1([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[cH:82][cH:83][cH:84][cH:85][cH:86]1.[c:87]1([P:88]([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[cH:101][cH:102][cH:103][cH:104][cH:105]1>>[c:2]1(-[c:35]2[n:36][cH:37][c:38]([F:41])[cH:39][cH:40]2)[cH:3][cH:4][c:5]([CH2:8][CH:9]([c:10]2[n:11]([CH3:21])[c:12]([CH2:15][C:16]([CH2:17][CH3:18])([CH3:19])[CH3:20])[cH:13][n:14]2)[N:22]([C:23]([O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)=[O:32])[CH3:33])[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-20a4d32dfdcc43248b06ec15f17479a1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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