Water → 5-Chloro-2-hydroxy-6-(piperidin-1-yl)-2,3-dihydrobenzofuran
Reaction equation
[CH2:19]([Al+:20][CH2:21][CH:22]([CH3:23])[CH3:24])[CH:25]([CH3:26])[CH3:27].[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][c:5]2[c:6]([cH:11]1)[CH2:7][C:8](=[O:10])[O:9]2.[H-:18].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH2:45].[S:28](=[O:29])(=[O:30])([OH:31])[OH:32]>>[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][c:5]2[c:6]([cH:11]1)[CH2:7][CH:8]([OH:10])[O:9]2Participants
8
Sources & evidence
- ORD record
- ord-fa5f9f28f9634017a9c61f4986f11c7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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