Benzene → 2-[2,5-Dimethoxy-3,6-bis(methoxymethoxy)phenyl]ethyl tert-butyldimethylsilyl ether

HRID 1207911Notes

Reaction equation

HRID 1207911 reaction equation
[C:24]([CH3:25])([CH3:26])([CH3:27])[Si:28]([CH3:29])([CH3:30])[O:31][CH2:32][CH2:33][Br:34].[CH3:1][O:2][c:3]1[c:4]([O:15][CH2:16][O:17][CH3:18])[cH:5][c:6]([O:13][CH3:14])[c:7]([O:9][CH2:10][O:11][CH3:12])[cH:8]1.[CH3:42][CH2:43][O:44][CH2:45][CH3:46].[CH3:53][N:54]([CH3:55])[P:56](=[O:57])([N:58]([CH3:59])[CH3:60])[N:61]([CH3:62])[CH3:63].[CH:19]([Li:20])([CH2:21][CH3:22])[CH3:23].[I-:36].[Na+:35].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[cH:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[CH3:1][O:2][c:3]1[c:4]([O:15][CH2:16][O:17][CH3:18])[c:5]([CH2:33][CH2:32][O:31][Si:28]([C:24]([CH3:25])([CH3:26])[CH3:27])([CH3:29])[CH3:30])[c:6]([O:13][CH3:14])[c:7]([O:9][CH2:10][O:11][CH3:12])[cH:8]1

Participants

10

Reactant 9

HCID 241BenzeneHCID 923Sodium ionHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 12679HexamethylphosphoramideHCID 30165Iodide IonHCID 3608067(2-Bromoethoxy)-tert-butyldimethylsilaneHCID 10061046HCID 10061046, compoundHCID 178418400CID 53628100

Product 1

HCID 197572472-[2,5-Dimethoxy-3,6-bis(methoxymethoxy)phenyl]ethyl tert-butyldimethylsilyl ether

Sources & evidence

ORD record
ord-00fdd1b5af1546f3bbaa45934cffe278
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…