Sodium ion → (1-(3-carboethoxypropyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine

HRID 1208233Notes

Reaction equation

HRID 1208233 reaction equation
[Br:26][CH2:27][CH2:28][CH2:29][C:30](=[O:31])[O:32][CH2:33][CH3:34].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[H-:24].[Na+:25].[nH:1]1[c:2]([NH:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[n:1]1([CH2:27][CH2:28][CH2:29][C:30](=[O:31])[O:32][CH2:33][CH3:34])[c:2]([NH:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 76300Ethyl 4-bromobutyrateHCID 166653HydrideHCID 22036999tert-Butyl 4-((1H-benzo[d]imidazol-2-yl)amino)piperidine-1-carboxylate

Product 1

HCID 22009256(1-(3-carboethoxypropyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine

Sources & evidence

ORD record
ord-e00d9c58c0c94a0d84e1ff71c6d6f475
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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