Bicarbonate Ion → [6-Cyclopropyl-2-(2-trifluoromethyl-phenyl)-pyrimidin-4-yl]-(1H-indazol-3-yl)-amine
Reaction equation
[C:32](=[O:33])([OH:34])[O-:35].[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[Cl:1][c:2]1[n:3][c:4](-[c:11]2[c:12]([C:17]([F:18])([F:19])[F:20])[cH:13][cH:14][cH:15][cH:16]2)[n:5][c:6]([CH:8]2[CH2:9][CH2:10]2)[cH:7]1.[Na+:36].[OH2:31].[nH:21]1[n:22][c:23]([NH2:30])[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]12>>[c:2]1([NH:30][c:23]2[n:22][nH:21][c:29]3[c:24]2[cH:25][cH:26][cH:27][cH:28]3)[n:3][c:4](-[c:11]2[c:12]([C:17]([F:18])([F:19])[F:20])[cH:13][cH:14][cH:15][cH:16]2)[n:5][c:6]([CH:8]2[CH2:9][CH2:10]2)[cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-97982401025e49af99f23f3c1b44881e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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