Hydrochloric Acid → N-[1-Phenyl-4-oxocyclohexyl]-2-[3,5-bis(trifluoromethyl)phenyl]propionamide

HRID 1208355Notes

Reaction equation

HRID 1208355 reaction equation
[CH3:16][CH:17]([C:18](=[O:19])[OH:20])[c:21]1[cH:22][c:23]([C:31]([F:32])([F:33])[F:34])[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1.[Cl:56][CH2:57][Cl:58].[ClH:41].[O:1]=[C:2]1[N:3]([P:4]([Cl:5])([N:6]2[CH2:7][CH2:8][O:9][C:10]2=[O:11])=[O:12])[CH2:13][CH2:14][O:15]1.[O:42]=[C:43]1[CH2:44][CH2:45][C:46]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)([NH2:55])[CH2:47][CH2:48]1.[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[CH3:16][CH:17]([C:18](=[O:19])[NH:55][C:46]1([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[CH2:45][CH2:44][C:43](=[O:42])[CH2:48][CH2:47]1)[c:21]1[cH:22][c:23]([C:31]([F:32])([F:33])[F:34])[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 6344DichloromethaneHCID 152842Bis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 115220582-(3,5-Bis(trifluoromethyl)phenyl)propanoic acidHCID 204533024-Amino-4-phenylcyclohexan-1-one

Product 1

HCID 21955177N-[1-Phenyl-4-oxocyclohexyl]-2-[3,5-bis(trifluoromethyl)phenyl]propionamide

Sources & evidence

ORD record
ord-ceb958799afe41889838c02df38095a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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