Dichloromethane → 1-[4-(2,6-Dinitro-phenyl)-piperazin-1-yl]-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propan-2-ol
Reaction equation
[C:1]([O:2][C:6](=[O:3])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([N+:23](=[O:24])[O-:25])[cH:16][cH:17][cH:18][c:19]2[N+:20](=[O:21])[O-:22])[CH2:12][CH2:13]1)([CH3:4])([CH3:5])[CH3:7].[CH3:33][S:34](=[O:35])(=[O:36])[N:37]1[CH2:38][c:39]2[c:40]([n:43]([CH2:56][CH:57]3[O:58][CH2:59]3)[n:44][c:45]2-[c:46]2[cH:47][cH:48][c:49]([C:52]([F:53])([F:54])[F:55])[cH:50][cH:51]2)[CH2:41][CH2:42]1.[Cl:60][CH2:61][Cl:62].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[CH2:6]([N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([N+:23](=[O:24])[O-:25])[cH:16][cH:17][cH:18][c:19]2[N+:20](=[O:21])[O-:22])[CH2:12][CH2:13]1)[CH:57]([CH2:56][n:43]1[c:40]2[c:39]([c:45](-[c:46]3[cH:47][cH:48][c:49]([C:52]([F:53])([F:54])[F:55])[cH:50][cH:51]3)[n:44]1)[CH2:38][N:37]([S:34]([CH3:33])(=[O:35])=[O:36])[CH2:42][CH2:41]2)[OH:58]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9428533226b74896b98e4d4ceeb29dda
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…