Dichloromethane → 2,3,4,5-Tetrahydro-1H-3-benzazepine-7-carbonitrile

HRID 1208768Notes

Reaction equation

HRID 1208768 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([C:19]#[N:20])[cH:18]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[Cl:28][CH2:29][Cl:30].[OH:21][C:22]([C:23]([F:24])([F:25])[F:26])=[O:27]>>[NH:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([C:19]#[N:20])[cH:18]2)[CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 18173275tert-Butyl 7-cyano-1,2,4,5-tetrahydro-3H-benzo[d]azepine-3-carboxylate

Product 1

HCID 181732792,3,4,5-Tetrahydro-1H-3-benzazepine-7-carbonitrile

Sources & evidence

ORD record
ord-c2d9c2b257584708a6b37919b3480b41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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