Acetic Acid → [5-(1-Cyclobutyl-piperidin-4-yloxy)-1H-indol-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanone
Reaction equation
[C:31]1(=[O:35])[CH2:32][CH2:33][CH2:34]1.[C:36]([O:37][BH3-:38])(=[O:39])[CH3:40].[CH3:27][C:28](=[O:29])[OH:30].[F:1][C:2]1([F:26])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[nH:11][c:12]3[cH:13][cH:14][c:15]([O:19][CH:20]4[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]4)[cH:16][c:17]3[cH:18]2)[CH2:6][CH2:7]1.[Na+:41].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[F:1][C:2]1([F:26])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[nH:11][c:12]3[cH:13][cH:14][c:15]([O:19][CH:20]4[CH2:21][CH2:22][N:23]([CH:31]5[CH2:32][CH2:33][CH2:34]5)[CH2:24][CH2:25]4)[cH:16][c:17]3[cH:18]2)[CH2:6][CH2:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b604fac261184afc8563fac298a41652
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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