Ethanol → 4-Chloro-3-(5-phenyl-1H-imidazol-2-yl) aniline

HRID 1209261Notes

Reaction equation

HRID 1209261 reaction equation
[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[CH3:35][CH2:36][OH:37].[Cl:1][c:2]1[c:3](-[c:11]2[nH:12][c:13](-[c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[cH:14][n:15]2)[cH:4][c:5]([N+:8]([O-:9])=[O:10])[cH:6][cH:7]1.[Na+:34].[OH-:33].[OH2:22].[OH2:23].[Sn:24]([Cl:25])[Cl:26]>>[Cl:1][c:2]1[c:3](-[c:11]2[nH:12][c:13](-[c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[cH:14][n:15]2)[cH:4][c:5]([NH2:8])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962Water2×HCID 8857Ethyl AcetateHCID 24479Stannous ChlorideHCID 580065202-(2-chloro-5-nitrophenyl)-5-phenyl-1H-imidazole

Product 1

HCID 498408204-Chloro-3-(5-phenyl-1H-imidazol-2-yl) aniline

Sources & evidence

ORD record
ord-e8310076ee264e0eb30aed7605623233
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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