Trifluoroacetic acid → 3-(4-Hydroxypiperidin-4-yl)quinolin-2(1H)-one

HRID 1209512Notes

Reaction equation

HRID 1209512 reaction equation
[OH:1][C:2]1([c:15]2[c:16](=[O:25])[nH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]3[cH:24]2)[CH2:3][CH2:4][N:5]([C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:6][CH2:7]1.[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[OH:1][C:2]1([c:15]2[c:16](=[O:25])[nH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]3[cH:24]2)[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 594243951,1-Dimethylethyl 4-(1,2-dihydro-2-oxo-3-quinolinyl)-4-hydroxy-1-piperidinecarboxylate

Product 1

HCID 594242883-(4-Hydroxypiperidin-4-yl)quinolin-2(1H)-one

Sources & evidence

ORD record
ord-2e06007655a1497d806d1a525d96e378
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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