Bicarbonate Ion → Methyl 2-(3-chloro-5-nitrophenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylate

HRID 1209955Notes

Reaction equation

HRID 1209955 reaction equation
[C:35](=[O:36])([OH:37])[O-:38].[Cl:1][c:2]1[cH:3][c:4]([CH:11]2[NH:12][c:13]3[cH:14][cH:15][c:16]([C:24](=[O:25])[O:26][CH3:27])[cH:17][c:18]3[CH:19]([OH:23])[C:20]2([CH3:21])[CH3:22])[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[Cl:40][CH2:41][Cl:42].[Na+:39].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[Cl:1][c:2]1[cH:3][c:4]([CH:11]2[NH:12][c:13]3[cH:14][cH:15][c:16]([C:24](=[O:25])[O:26][CH3:27])[cH:17][c:18]3[CH2:19][C:20]2([CH3:21])[CH3:22])[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67442943Methyl 2-(3-chloro-5-nitrophenyl)-4-hydroxy-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylate

Product 1

HCID 67439798Methyl 2-(3-chloro-5-nitrophenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylate

Sources & evidence

ORD record
ord-772ed64ea2154ecfbdbb2b38bb60828a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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