Water → 5-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)pyridin-2-amine

HRID 1210017Notes

Reaction equation

HRID 1210017 reaction equation
[C:32](=[O:33])([O-:34])[O-:35].[CH3:17][n:18]1[n:19][cH:20][c:21]([B:23]2[O:24][C:25]([CH3:26])([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31]2)[cH:22]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][c:12]([NH2:15])[n:13][cH:14]2)[cH:7]1.[Cs+:36].[Cs+:37].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42].[OH2:16]>>[c:2]1(-[c:21]2[cH:20][n:19][n:18]([CH3:17])[cH:22]2)[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][c:12]([NH2:15])[n:13][cH:14]2)[cH:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 27739871-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 593227885-(2-Chloropyridin-4-yloxy)pyridin-2-amine

Product 1

HCID 593227775-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)pyridin-2-amine

Sources & evidence

ORD record
ord-7c3fdf75f80b4773a679a7b45406d4fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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