3,4-Diaminopyridine → N-(4-amino-3-pyridinyl)-N'-[2-[4-[[1-(2-furanylmethyl)-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]thiourea

HRID 1210083Notes

Reaction equation

HRID 1210083 reaction equation
[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[n:1]1[cH:2][c:3]([NH2:8])[c:4]([NH2:7])[cH:5][cH:6]1.[o:9]1[c:10]([CH2:14][n:15]2[c:16]([NH:24][CH:25]3[CH2:26][CH2:27][N:28]([CH2:31][CH2:32][N:33]=[C:34]=[S:35])[CH2:29][CH2:30]3)[n:17][c:18]3[c:19]2[cH:20][cH:21][cH:22][cH:23]3)[cH:11][cH:12][cH:13]1>>[n:1]1[cH:2][c:3]([NH:8][C:34]([NH:33][CH2:32][CH2:31][N:28]2[CH2:27][CH2:26][CH:25]([NH:24][c:16]3[n:15]([CH2:14][c:10]4[o:9][cH:13][cH:12][cH:11]4)[c:19]4[c:18]([n:17]3)[cH:23][cH:22][cH:21][cH:20]4)[CH2:30][CH2:29]2)=[S:35])[c:4]([NH2:7])[cH:5][cH:6]1

Participants

4

Reactant 3

HCID 59183,4-DiaminopyridineHCID 8028TetrahydrofuranHCID 148353051-(2-furanylmethyl)-N-[1-(2-isothiocyanatoethyl)-4-piperidinyl]-1H-benzimidazol-2-amine

Product 1

HCID 14835314N-(4-amino-3-pyridinyl)-N'-[2-[4-[[1-(2-furanylmethyl)-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]thiourea

Sources & evidence

ORD record
ord-0e375010714248f193acb8582f4d7b3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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