Diisopropylamine → Tert-butyl 3-cyano-3-(fluoromethyl)azetidine-1-carboxylate
Reaction equation
[Br:26][CH2:27][F:28].[C:13](#[N:14])[CH:15]1[CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:8][CH2:9][CH2:10][CH2:11][Li:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7]>>[C:13](#[N:14])[C:15]1([CH2:27][F:28])[CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]1Participants
6
Sources & evidence
- ORD record
- ord-b185da7e191c43aab73eddcb220cd760
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…