Potassium Cation → 5-chloro-N-[2-(dimethylamino)ethyl]-N-methyl-6-({4-[(1-methyl-1H-pyrazol-3-yl)amino]quinazolin-6-yl}oxy)nicotinamide
Reaction equation
[CH3:18][C:19]([CH3:20])([O-:21])[CH3:22].[CH3:24][N:25]([CH3:26])[C:27](=[O:28])[CH3:29].[CH3:30][n:31]1[n:32][c:33]([NH:36][c:37]2[n:38][cH:39][n:40][c:41]3[cH:42][cH:43][c:44]([OH:47])[cH:45][c:46]23)[cH:34][cH:35]1.[Cl:1][c:2]1[c:3]([Cl:17])[n:4][cH:5][c:6]([C:7](=[O:8])[N:9]([CH3:10])[CH2:11][CH2:12][N:13]([CH3:14])[CH3:15])[cH:16]1.[K+:23].[OH2:48]>>[Cl:1][c:2]1[c:3]([O:47][c:44]2[cH:43][cH:42][c:41]3[n:40][cH:39][n:38][c:37]([NH:36][c:33]4[n:32][n:31]([CH3:30])[cH:35][cH:34]4)[c:46]3[cH:45]2)[n:4][cH:5][c:6]([C:7](=[O:8])[N:9]([CH3:10])[CH2:11][CH2:12][N:13]([CH3:14])[CH3:15])[cH:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-720bff89d9764151a9be01ee9659f464
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…