Toluene → alpha-(2-(1-Pyrrolidinyl)ethyl)-alpha-(p-tolyl)pyridine-2-methanol
Reaction equation
[Br:6][c:7]1[cH:8][cH:9][cH:10][cH:11][n:12]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:13][c:14]1[cH:15][cH:16][c:17]([C:20]([CH2:21][CH2:22][N:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)=[O:28])[cH:18][cH:19]1.[CH3:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34].[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[c:7]1([C:20]([c:17]2[cH:16][cH:15][c:14]([CH3:13])[cH:19][cH:18]2)([CH2:21][CH2:22][N:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)[OH:28])[cH:8][cH:9][cH:10][cH:11][n:12]1Participants
6
Sources & evidence
- ORD record
- ord-d815a3764d134df78f71dd6034cc1152
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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