Sodium ion → benzyl 4-[4-(2-methoxy-3-phenoxypropoxy)phenyl]-3-[[4-(3-methoxypropyl)-3-oxo-1,4-benzoxazin-6-yl]methoxy]piperidine-1-carboxylate

HRID 1210500Notes

Reaction equation

HRID 1210500 reaction equation
[CH3:55][I:56].[H-:54].[Na+:53].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1.[OH:1][CH:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([O:27][CH2:28][c:29]3[cH:30][cH:31][c:32]4[c:33]([cH:44]3)[N:34]([CH2:39][CH2:40][CH2:41][O:42][CH3:43])[C:35](=[O:38])[CH2:36][O:37]4)[CH2:13][N:14]([C:17](=[O:18])[O:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:15][CH2:16]2)[cH:9][cH:10]1)[CH2:45][O:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[O:1]([CH:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([O:27][CH2:28][c:29]3[cH:30][cH:31][c:32]4[c:33]([cH:44]3)[N:34]([CH2:39][CH2:40][CH2:41][O:42][CH3:43])[C:35](=[O:38])[CH2:36][O:37]4)[CH2:13][N:14]([C:17](=[O:18])[O:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:15][CH2:16]2)[cH:9][cH:10]1)[CH2:45][O:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1)[CH3:55]

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 166653HydrideHCID 178495244HCID 178495244, compound

Product 1

HCID 178495243benzyl 4-[4-(2-methoxy-3-phenoxypropoxy)phenyl]-3-[[4-(3-methoxypropyl)-3-oxo-1,4-benzoxazin-6-yl]methoxy]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-5cbc9ddb9c8547c690920608a24ba63b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…