Dichloromethane → Tert-butyl 4-[4-(chloromethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
Reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:28][S:29]([Cl:30])(=[O:31])=[O:32].[Cl:33][CH2:34][Cl:35].[OH:1][CH2:2][c:3]1[n:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[s:6][cH:7]1>>[CH2:2]([c:3]1[n:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[s:6][cH:7]1)[Cl:30]Participants
5
Sources & evidence
- ORD record
- ord-96c78c5333164bb7a60b548744ca5592
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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