Hydrochloric Acid → 2-N-[4-(1,3-oxazol-5-yl)phenyl]-4-N-(oxolan-2-ylmethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

HRID 121055Notes

Reaction equation

HRID 121055 reaction equation
[CH3:38][OH:39].[ClH:37].[o:1]1[cH:2][n:3][cH:4][c:5]1-[c:6]1[cH:7][cH:8][c:9]([NH:12][c:13]2[n:14][c:15]([NH:30][CH2:31][CH:32]3[O:33][CH2:34][CH2:35][CH2:36]3)[c:16]3[c:17]([n:18]2)[CH2:19][CH2:20][N:21]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:22]3)[cH:10][cH:11]1>>[o:1]1[cH:2][n:3][cH:4][c:5]1-[c:6]1[cH:7][cH:8][c:9]([NH:12][c:13]2[n:14][c:15]([NH:30][CH2:31][CH:32]3[O:33][CH2:34][CH2:35][CH2:36]3)[c:16]3[c:17]([n:18]2)[CH2:19][CH2:20][NH:21][CH2:22]3)[cH:10][cH:11]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59333769tert-butyl 2-[4-(1,3-oxazol-5-yl)anilino]-4-(oxolan-2-ylmethylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate

Product 1

HCID 593337922-N-[4-(1,3-oxazol-5-yl)phenyl]-4-N-(oxolan-2-ylmethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-15cc7eae6b3c4ebaa608779c4f3c9602
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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