Tetrahydrofuran → 2-fluoro-4-[1-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-4-yl)-vinyl]-benzoic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([F:37])[cH:6][c:7]([C:10](=[CH:11][CH:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][c:24]([F:26])[cH:25]3)[n:27]2[S:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)(=[O:35])=[O:36])[cH:8][cH:9]1)=[O:38].[CH3:40][CH2:41][CH2:42][CH2:43][N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56].[F-:39].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([F:37])[cH:6][c:7]([C:10](=[CH:11][CH:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][c:24]([F:26])[cH:25]3)[nH:27]2)[cH:8][cH:9]1)=[O:38]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-97cd4c2111234770bd9b27382a16ef17
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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