Dichloromethane → N-(5-acetyl-2-chloro-phenyl)-3,4-dimethoxy-benzenesulfonamide

HRID 1211068Notes

Reaction equation

HRID 1211068 reaction equation
[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[Cl:1][c:2]1[c:3]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]2)[cH:4][c:5]([CH:8]([CH3:9])[OH:10])[cH:6][cH:7]1.[Cl:25][CH2:26][Cl:27].[O:33]=[Mn:34]=[O:35]>>[Cl:1][c:2]1[c:3]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]2)[cH:4][c:5]([C:8]([CH3:9])=[O:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 14801Manganese dioxideHCID 57511305N-[2-chloro-5-(1-hydroxy-ethyl)-phenyl]-3,4-dimethoxy-benzenesulfonamide

Product 1

HCID 57511306N-(5-acetyl-2-chloro-phenyl)-3,4-dimethoxy-benzenesulfonamide

Sources & evidence

ORD record
ord-0229954c799048bf95605a03426657a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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