Pyridine → N-(3-Methylisoquinolin-5-yl)-N'-[(1-(5-trifluoromethyl-2-pyridyl)azetidin-3-yl)]urea
Reaction equation
[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl:19][C:20](=[O:21])[O:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[Cl:51][CH2:52][Cl:53].[F:36][C:37]([c:38]1[cH:39][cH:40][c:41]([N:44]2[CH2:45][CH:46]([NH2:48])[CH2:47]2)[n:42][cH:43]1)([F:49])[F:50].[NH2:1][c:2]1[c:3]2[cH:4][c:5]([CH3:12])[n:6][cH:7][c:8]2[cH:9][cH:10][cH:11]1.[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1>>[NH:1]([c:2]1[c:3]2[cH:4][c:5]([CH3:12])[n:6][cH:7][c:8]2[cH:9][cH:10][cH:11]1)[C:20](=[O:21])[NH:48][CH:46]1[CH2:45][N:44]([c:41]2[cH:40][cH:39][c:38]([C:37]([F:36])([F:49])[F:50])[cH:43][n:42]2)[CH2:47]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ef26b71b909743b19418b71c59290258
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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