Hydrochloric Acid → 7-[[[1-(1,3-Benzoxazol-2-yl)-2-phenylpiperidin-3-yl]amino]methyl]-6-methoxy-1-methyl-3,4-dihydroquinolin-2-one

HRID 1211198Notes

Reaction equation

HRID 1211198 reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[CH2:47]1[O:48][CH2:49][CH2:50][O:51][CH2:52]1.[CH3:3][O:4][c:5]1[cH:6][c:7]2[c:12]([cH:13][c:14]1[CH2:15][NH:16][CH:17]1[CH:18]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[NH:19][CH2:20][CH2:21][CH2:22]1)[N:11]([CH3:29])[C:10](=[O:30])[CH2:9][CH2:8]2.[Cl:37][c:38]1[o:39][c:40]2[c:41]([n:42]1)[cH:43][cH:44][cH:45][cH:46]2.[ClH:1].[ClH:2].[K+:35].[K+:36]>>[CH3:3][O:4][c:5]1[cH:6][c:7]2[c:12]([cH:13][c:14]1[CH2:15][NH:16][CH:17]1[CH:18]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[N:19]([c:38]3[o:39][c:40]4[c:41]([n:42]3)[cH:43][cH:44][cH:45][cH:46]4)[CH2:20][CH2:21][CH2:22]1)[N:11]([CH3:29])[C:10](=[O:30])[CH2:9][CH2:8]2

Participants

7

Reactant 6

HCID 313Hydrochloric Acid2×HCID 813Potassium Cation2×HCID 119862-ChlorobenzoxazoleHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 101997316-methoxy-1-methyl-7-[(2-phenyl-piperidin-3-yl-amino)-methyl]-3,4-dihydro-1H-quinolin-2-one

Product 1

HCID 696545637-[[[1-(1,3-Benzoxazol-2-yl)-2-phenylpiperidin-3-yl]amino]methyl]-6-methoxy-1-methyl-3,4-dihydroquinolin-2-one

Sources & evidence

ORD record
ord-8d5ded4679724ab9827565987fe60d5f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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