Hydrochloric Acid → (+/-)-7-Chloro-3-(2,2,2-trifluoroacetyl)-6-(2-phenyl-pyrrolidin-1-yl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[C:37]([BH3-:38])#[N:39].[CH3:34][OH:35].[CH3:44][CH2:45][O:46][CH2:47][CH3:48].[Cl:1][c:2]1[c:3]([NH:19][CH2:20][CH2:21][CH2:22][C:23]2([c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[O:24][CH2:25][CH2:26][O:27]2)[c:4]2[c:5]([cH:17][cH:18]1)[CH2:6][CH2:7][N:8]([C:11]([C:12]([F:13])([F:14])[F:15])=[O:16])[CH2:9][CH2:10]2.[Cl:41][CH2:42][Cl:43].[ClH:36].[Na+:40]>>[Cl:1][c:2]1[c:3]([N:19]2[CH2:20][CH2:21][CH2:22][CH:23]2[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:4]2[c:5]([cH:17][cH:18]1)[CH2:6][CH2:7][N:8]([C:11]([C:12]([F:13])([F:14])[F:15])=[O:16])[CH2:9][CH2:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-cf93fcaaa25a458e92ccb9d65c7edcb8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…