Dichloromethane → {4-[(3-Chloro-4-fluoro-benzo[b]thiophene-2-carbonyl)-(2-methoxy-5-pyridin-3-yl-benzyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[c:17]([O:28][CH3:29])[cH:18][cH:19][c:20](-[c:22]3[cH:23][n:24][cH:25][cH:26][cH:27]3)[cH:21]2)[CH2:12][CH2:13]1)=[O:30].[CH2:54]([Cl:55])[Cl:56].[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:40][c:41]1[c:42]2[c:43]([s:44][c:45]1[C:46](=[O:47])[Cl:48])[cH:49][cH:50][cH:51][c:52]2[F:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[c:17]([O:28][CH3:29])[cH:18][cH:19][c:20](-[c:22]3[cH:23][n:24][cH:25][cH:26][cH:27]3)[cH:21]2)[C:46]([c:45]2[c:41]([Cl:40])[c:42]3[c:43]([s:44]2)[cH:49][cH:50][cH:51][c:52]3[F:53])=[O:47])[CH2:12][CH2:13]1)=[O:30]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0d9884fec0cb4defb804e5db7f3163b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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