Dimethylformamide → 4-(4-Fluoro-2-methylindol-5-yloxy)-7-methoxy-6-(3-(4-methylsulphonylpiperazin-1yl)propoxy)quinazoline
Reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][c:8]2[c:9]([O:18][c:19]3[c:20]([F:29])[c:21]4[cH:22][c:23]([CH3:28])[nH:24][c:25]4[cH:26][cH:27]3)[n:10][cH:11][n:12][c:13]2[cH:14][c:15]1[O:16][CH3:17].[CH3:30][S:31](=[O:32])(=[O:33])[N:34]1[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[cH:7][c:8]2[c:9]([O:18][c:19]3[c:20]([F:29])[c:21]4[cH:22][c:23]([CH3:28])[nH:24][c:25]4[cH:26][cH:27]3)[n:10][cH:11][n:12][c:13]2[cH:14][c:15]1[O:16][CH3:17])[N:37]1[CH2:36][CH2:35][N:34]([S:31]([CH3:30])(=[O:32])=[O:33])[CH2:39][CH2:38]1Participants
4
Sources & evidence
- ORD record
- ord-3f36f62cc40c48dd95d1620757ab37b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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