Hydrochloric Acid → Ethyl [4-(1-hydroxy-2-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)-2-methylphenoxy]acetate

HRID 1211573Notes

Reaction equation

HRID 1211573 reaction equation
[BH4-:34].[CH3:1][c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12][c:13]([C:15]([CH2:16][c:17]2[c:18]([CH3:32])[n:19][c:20](-[c:22]3[cH:23][cH:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[s:21]2)=[O:33])[cH:14]1.[CH3:38][CH2:39][OH:40].[ClH:36].[Na+:35].[OH2:37]>>[CH3:1][c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12][c:13]([CH:15]([CH2:16][c:17]2[c:18]([CH3:32])[n:19][c:20](-[c:22]3[cH:23][cH:24][c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[s:21]2)[OH:33])[cH:14]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 962WaterHCID 28123BorohydrideHCID 58824797Ethyl [2-methyl-4-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}acetyl)phenoxy]acetate

Product 1

HCID 17972190Ethyl [4-(1-hydroxy-2-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)-2-methylphenoxy]acetate

Sources & evidence

ORD record
ord-ebce6dc1e68f49f2bda3cbb1915ebbb5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…