Dichloromethane → 1-(2-Fluoro-4-methanesulfonyl-phenyl)-piperidin-4-one O-piperidin-4-yl-oxime

HRID 1211582Notes

Reaction equation

HRID 1211582 reaction equation
[Cl:40][CH2:41][Cl:42].[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][C:15](=[N:18][O:19][CH:20]3[CH2:21][CH2:22][N:23]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:24][CH2:25]3)[CH2:16][CH2:17]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1.[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39]>>[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][C:15](=[N:18][O:19][CH:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[CH2:16][CH2:17]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 49853805HCID 49853805, compound

Product 1

HCID 866550221-(2-Fluoro-4-methanesulfonyl-phenyl)-piperidin-4-one O-piperidin-4-yl-oxime

Sources & evidence

ORD record
ord-7c210c49f6374462839091fffd47acd5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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