Tetrahydrofuran → 1-[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-propan-1-one
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[CH:6]1[CH2:7][N:8]([CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:9][CH:10]1[c:11]1[cH:12][c:13]([Cl:18])[c:14]([Cl:17])[cH:15][cH:16]1)[CH3:26].[Li:27][CH2:28][CH3:29]>>[C:4](=[O:5])([CH:6]1[CH2:7][N:8]([CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:9][CH:10]1[c:11]1[cH:12][c:13]([Cl:18])[c:14]([Cl:17])[cH:15][cH:16]1)[CH2:28][CH3:29]Participants
4
Sources & evidence
- ORD record
- ord-785d992255924007ad7eebbc9bb087d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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