Dimethyl Sulfoxide → N,N-dibenzyl-8-(2-methoxypyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

HRID 1211718Notes

Reaction equation

HRID 1211718 reaction equation
[CH2:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)[N:19]([CH:20]1[CH2:21][c:22]2[c:23]([Br:30])[cH:24][cH:25][cH:26][c:27]2[CH2:28][CH2:29]1)[CH2:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH3:1][O:2][c:3]1[n:4][cH:5][c:6]([B:9]([OH:10])[OH:11])[cH:7][n:8]1.[CH3:38][S:39]([CH3:40])=[O:41]>>[CH3:1][O:2][c:3]1[n:4][cH:5][c:6](-[c:23]2[c:22]3[c:27]([cH:26][cH:25][cH:24]2)[CH2:28][CH2:29][CH:20]([N:19]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[CH2:21]3)[cH:7][n:8]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 27367782-Methoxypyrimidine-5-boronic acidHCID 18622522N,N-dibenzyl-8-bromo-1,2,3,4-tetrahydronaphthalen-2-amine

Product 1

HCID 140551728N,N-dibenzyl-8-(2-methoxypyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

Sources & evidence

ORD record
ord-d9c3dc2ba2db496b9e5913ba4734ade4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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