Methanol → 6-(6-(3-Ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-yl)-1-((1-(2-morpholinoethyl)pyrrolidin-3-yl)methyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Reaction equation
[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:42]2[s:43][cH:44][c:45]([C:47]([F:48])([F:49])[F:50])[n:46]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:41])[c:16]([C:36](=[O:37])[O:38][CH2:39][CH3:40])[cH:17][n:18]([CH2:22][CH:23]4[CH2:24][N:25]([CH2:28][CH2:29][N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[CH2:26][CH2:27]4)[c:19]3[cH:20][cH:21]2)[cH:10][n:11]1)=[O:51].[CH3:54][OH:55].[Na+:53].[O:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1.[OH-:52]>>[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:42]2[s:43][cH:44][c:45]([C:47]([F:48])([F:49])[F:50])[n:46]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:41])[c:16]([C:36](=[O:37])[OH:38])[cH:17][n:18]([CH2:22][CH:23]4[CH2:24][N:25]([CH2:28][CH2:29][N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[CH2:26][CH2:27]4)[c:19]3[cH:20][cH:21]2)[cH:10][n:11]1)=[O:51]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b0e968cc2891481da7520d3a9766676e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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