Dimethyl Sulfoxide → Tert-butyl 4-cyano-2-methylpyrrolidine-1-carboxylate

HRID 1211823Notes

Reaction equation

HRID 1211823 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:18])[CH2:10][CH:11]([O:13][S:14]([CH3:15])(=[O:16])=[O:17])[CH2:12]1.[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[CH3:29][S:30](=[O:31])[CH3:32].[Na:19][C:20]#[N:21].[OH2:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:18])[CH2:10][CH:11]([C:20]#[N:21])[CH2:12]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 8857Ethyl AcetateHCID 197903964-Methanesulfonyloxy-2-methyl-pyrrolidine-1-carboxylic Acid T-butyl EsterHCID 178511850HCID 178511850, compound

Product 1

HCID 19900265Tert-butyl 4-cyano-2-methylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-38782639ff694519be90d65ea7977d9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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