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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 121260Generated: November 2, 2026

Hydrochloric Acid → (2RS,4SR)-4-(3,5-difluorophenyl)-4-hydroxy-2-methyltetrahydropyran

https://huagongshe.com/reaction/121260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,2-DibromoethaneHCID 7839—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-3,5-difluorobenzeneHCID 136313—
ReactantMagnesiumHCID 5462224—
Reactant2-Methyltetrahydro-4H-pyran-4-oneHCID 10374434—
Product(2RS,4SR)-4-(3,5-difluorophenyl)-4-hydroxy-2-methyltetrahydropyranHCID 22413801—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-b310d1ce9e404170ab5e715c0e7ce10a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)