Hydrochloric Acid → (2RS,4SR)-4-(3,5-difluorophenyl)-4-hydroxy-2-methyltetrahydropyran
Reaction equation
[Br:10][CH2:11][CH2:12][Br:13].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:15][CH:16]1[O:17][CH2:18][CH2:19][C:20](=[O:22])[CH2:21]1.[ClH:23].[F:1][c:2]1[cH:3][c:4]([Br:9])[cH:5][c:6]([F:8])[cH:7]1.[Mg:14]>>[F:1][c:2]1[cH:3][c:4]([C:20]2([OH:22])[CH2:19][CH2:18][O:17][CH:16]([CH3:15])[CH2:21]2)[cH:5][c:6]([F:8])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-b310d1ce9e404170ab5e715c0e7ce10a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…