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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1212705Generated: October 31, 2026

Dichloromethane → 7-(4-Bromo-2-fluorophenyl)-4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/1212705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
Reactant1-Methylethyl 4-((7-(2-Fluoro-4-(methylsulfonyl)phenyl)-6,7-dihydro-5H-pyrrolo(2,3-d)pyrimidin-4-yl)oxy)-1-piperidinecarboxylateHCID 23653563—
Reactanttert-butyl N-(4-bromo-2-fluorophenyl)-N-[6-chloro-5-(2-hydroxyethyl)pyrimidin-4-yl]carbamateHCID 86637383—
Product7-(4-Bromo-2-fluorophenyl)-4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidineHCID 86637385—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-2be535c52a034e3daafb2f76b201b548
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)