Methanol → racemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-1'-[(hydroxycarbonyl)-methyl]-2'-(2-methylphenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione
Reaction equation
[CH3:37][OH:38].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:30]2[c:31]([CH3:36])[cH:32][cH:33][cH:34][cH:35]2)[N:13]([CH2:25][C:26](=[O:27])[O:28][CH3:29])[C:14](=[O:24])[CH2:15][CH:16]1[c:17]1[cH:18][c:19]([Cl:23])[cH:20][cH:21][cH:22]1.[Na+:40].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH-:39]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:30]2[c:31]([CH3:36])[cH:32][cH:33][cH:34][cH:35]2)[N:13]([CH2:25][C:26](=[O:27])[OH:28])[C:14](=[O:24])[CH2:15][CH:16]1[c:17]1[cH:18][c:19]([Cl:23])[cH:20][cH:21][cH:22]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7e6fcaf0426d4c098b84ebf885c24644
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…