Dichloromethane → 5-(4-Phenoxy-phenyl)-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

HRID 1212782Notes

Reaction equation

HRID 1212782 reaction equation
[Cl:43][CH2:44][Cl:45].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:24]1[CH2:25][N:26]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:27][CH2:28]1)[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1.[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1)[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22736315HCID 22736315, compound

Product 1

HCID 101383765-(4-Phenoxy-phenyl)-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

Sources & evidence

ORD record
ord-f2b8dc291b4a43ea8be2f0710ecd9f32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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