Sodium ion → N-(5-chloro-7-iodo-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Reaction equation
[CH3:36][Si:37]([N-:38][Si:39]([CH3:40])([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:24][c:25]1[c:26]([NH2:35])[c:27]2[c:28]([c:32]([I:34])[cH:33]1)[O:29][CH2:30][O:31]2.[Na+:45].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[c:2]1([NH:35][c:26]2[c:25]([Cl:24])[cH:33][c:32]([I:34])[c:28]3[c:27]2[O:31][CH2:30][O:29]3)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-97ae0007666b4f8ab89c9e2b4c4021e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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