Tetrahydrofuran → tert-Butyl 3-[2-(2-fluoropyridin-3-yl)-2-hydroxyethyl]pyridin-4-ylcarbamate
Reaction equation
[CH2:16]([Li:17])[CH2:18][CH2:19][CH3:20].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15].[F:21][c:22]1[c:23]([CH:24]=[O:25])[cH:26][cH:27][cH:28][n:29]1>>[CH2:1]([c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[CH:24]([c:23]1[c:22]([F:21])[n:29][cH:28][cH:27][cH:26]1)[OH:25]Participants
5
Sources & evidence
- ORD record
- ord-8aac5cd5399b478da23e04f6c7f21d2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…