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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1213451Generated: October 31, 2026

Dichloromethane → 7-Chloro-5-piperidin-4-ylmethyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one

https://huagongshe.com/reaction/1213451

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-[7-Chloro-1-oxo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-1H-isoindol-5-ylmethyl]-piperidine-1-carboxylic acid tert-butyl esterHCID 57949697—
Product7-Chloro-5-piperidin-4-ylmethyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-oneHCID 57949297—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-05b66b4275994c1b8ae8db26e2c81674
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)