Iron → Ivabradine, (+-)-

HRID 1213455Notes

Reaction equation

HRID 1213455 reaction equation
[CH3:16][O:17][c:18]1[cH:19][c:20]2[c:21]([cH:32][c:33]1[O:34][CH3:35])[CH2:22][C:23](=[O:31])[N:24]([CH2:27][CH2:28][CH:29]=[O:30])[CH2:25][CH2:26]2.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:8]([cH:9][c:10]1[O:11][CH3:12])[CH:7]([CH2:13][NH:14][CH3:15])[CH2:6]2.[Fe:36]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:8]([cH:9][c:10]1[O:11][CH3:12])[CH:7]([CH2:13][N:14]([CH3:15])[CH2:29][CH2:28][CH2:27][N:24]1[C:23](=[O:31])[CH2:22][c:21]3[c:20]([cH:19][c:18]([O:17][CH3:16])[c:33]([O:34][CH3:35])[cH:32]3)[CH2:26][CH2:25]1)[CH2:6]2

Participants

4

Reactant 3

HCID 23925IronHCID 201441843-(7,8-Dimethoxy-2-oxo-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-propionaldehydeHCID 222623581-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine

Product 1

HCID 6426711Ivabradine, (+-)-

Sources & evidence

ORD record
ord-77e8e5cfc165485ca4ca0b126c98ed58
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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