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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1213592Generated: October 31, 2026

[2-(2-{4-[3-(2-Hydroxy-5-methyl-phenyl)-1-methyl-1H-pyrazol-4-ylethynyl]-phenylcarbamoyl}-piperidin-1-yl)-2-oxo-1-phenyl-ethyl]-carbamic acid tert-butyl ester → [2-(3-{4-[3-(5-Chloro-2-hydroxy-phenyl)-1-methyl-1H-pyrazol-4-ylethynyl]-phenylcarbamoyl}-morpholin-4-yl)-2-oxo-1-phenyl-ethyl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1213592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[2-(2-{4-[3-(2-Hydroxy-5-methyl-phenyl)-1-methyl-1H-pyrazol-4-ylethynyl]-phenylcarbamoyl}-piperidin-1-yl)-2-oxo-1-phenyl-ethyl]-carbamic acid tert-butyl esterHCID 135974951—
ReactantMorpholine-3-carboxylic acid {4-[3-(5-chloro-2-hydroxy-phenyl)-1-methyl-1H-pyrazol-4-ylethynyl]-phenyl}-amideHCID 136346686—
Product[2-(3-{4-[3-(5-Chloro-2-hydroxy-phenyl)-1-methyl-1H-pyrazol-4-ylethynyl]-phenylcarbamoyl}-morpholin-4-yl)-2-oxo-1-phenyl-ethyl]-carbamic acid tert-butyl esterHCID 136346688—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-965030287f4f4b00922bf9839e665f43
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)