Dimethylformamide → tert-butyl 4-[4-[(6-iodo-1,3-dioxoisoquinolin-4-ylidene)methylamino]phenyl]piperazine-1-carboxylate

HRID 1213629Notes

Reaction equation

HRID 1213629 reaction equation
[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[I:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[NH:7][C:6](=[O:13])[C:5]2=[CH:14][O:15][CH3:16].[NH2:17][c:18]1[cH:19][cH:20][c:21]([N:24]2[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]2)[cH:22][cH:23]1>>[I:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[NH:7][C:6](=[O:13])[C:5]2=[CH:14][NH:17][c:18]1[cH:19][cH:20][c:21]([N:24]2[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]2)[cH:22][cH:23]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 11011301tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylateHCID 686910194-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione

Product 1

HCID 178452240tert-butyl 4-[4-[(6-iodo-1,3-dioxoisoquinolin-4-ylidene)methylamino]phenyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-9ceebd14ad774126967f4233ba57fd9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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